Pioneering Inactivated In Ovo Vaccination for Avian Colibacillosis

2026 May, SatPublications

We’re proud to share our latest publication in MDPI Animals:​
“Safety, Immunogenicity, and Vaccine Compatibility of a Trivalent Inactivated In Ovo Nanovaccine Against Avian Colibacillosis in Broilers.”​
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This is the first report of an inactivated in ovo vaccine against avian colibacillosis.​
Our study demonstrates:​
• Strong immunogenicity​ of the vaccine
• Compatibility with commonly used live viral vaccines​
• A scalable approach enabled by Vaxinano’s nanovaccine platform for in ovo combined vaccines​
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Why it matters:​
In ovo vaccination allows protection before hatch, ensuring early, uniform immunity while reducing handling, labor, and variability in commercial hatcheries.​
This work represents an important step toward innovative vaccination strategies and contributes to tackling global challenges like antimicrobial resistance.​
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We also thank the International Development Research Centre (IDRC) for their support through the InnoVet AMR 1.0 program, and Najete Safini, PhD, MSc,BSc Safini, Renée Larocque, and Elizabeth Mohan!

Find the link to the publication here: https://lnkd.in/eNXraxJk